(3R,4R,5S)-5-(Acetamidomethyl)-N-benzyl-3,4-dihydroxytetrahydrofuran-3-carboxamide
نویسندگان
چکیده
منابع مشابه
(S)-N-Benzyl-2-methyl-1,2,3,4-tetrahydroisoquinoline-3-carboxamide
The structure of the title compound, C(18)H(20)N(2)O, at 173 K has hexa-gonal (P6(1)) symmetry. The N-containing six-membered ring assumes a half-chair conformation. In the crystal, inter-molecular N-H⋯O hydrogen bonding via the amide groups cross-link the mol-ecules along the a axis. The absolute configuration was confirmed by 2D NMR studies.
متن کامل(S)-2-Benzyl-N-(2,6-diisopropylphenyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide
The asymmetric unit of the title compound, C(29)H(34)N(2)O, contains two mol-ecules in which the N-containing six-membered rings assume different conformations viz. half-chair and envelope. Inter-molecular N-H⋯O hydrogen bonding via the amide groups cross-link the mol-ecules in the crystal structure.
متن کامل(3R,4R,5R)-5-(Acetamidomethyl)-N-benzyl-3,4-dihydroxytetrahydrofuran-3-carboxamide
X-ray crystallographic analysis with Cu Kα radiation established the relative configurations of the stereogenic centers in the title compound, C(15)H(20)N(2)O(5), and clarified mechanistic ambiguities in the synthesis. The conformation of the five-membered ring approximates twisted, about a C-O bond. The absolute configuration of this carbon-branched dipeptide isostere was known based on the us...
متن کامل(4S)-4-Benzyl-N-{[(4S)-4-benzyl-2-oxo-1,3-oxazolidin-3-yl]sulfonyl}-2-oxo-1,3-oxazolidine-3-carboxamide
The title compound, C(21)H(21)N(3)O(7)S, contains an oxazolidinone ring and a sulfonamide group, both characteristic for biologically and pharrmaceutically active compounds. Both stereogenic centres reveal an S absolute configuration. The two oxazolidinone rings are in an envelope conformation with the methyl-ene carbon flap atoms deviating by 0.428 (1) and 0.364 (2) Å from the best least-squar...
متن کاملN-tert-Butyl-3-hydroxy-5-androstene-17-carboxamide monohydrate
In the title compound, C(24)H(39)NO(2)·H(2)O, the A and C rings of the pregnolene derivative sterol adopt chair conformations, with the B ring in a flattened chair conformation and the five-membered ring in an envelope conformation twisted about the C/D ring junction. The N-tert-butyl-carboxamide substituent is equatorial. The 3β-hydr-oxy H atom and one H atom of the water mol-ecule are disorde...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Acta Crystallographica Section E Structure Reports Online
سال: 2005
ISSN: 1600-5368
DOI: 10.1107/s1600536805001467